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Methotrexate

Methotrexate

Product Description
CAT No.
ALN-M019035
CAS No.
59-05-2
Mol. F.
C20H22N8O5
Mol. Wt.
454.4
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RFQ
Chemical Name : (4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid
Smiles : O=C(O)[C@@H](NC(C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3N=C2)C)C=C1)=O)CCC(O)=O
Inchi : InChI=1S/C20H26N4O2/c21-11-13-23(19(25)17-7-3-1-4-8-17)15-16-24(14-12-22)20(26)18-9-5-2-6-10-18/h1-10H,11-16,21-22H2

Identification and Quantitation of Impurities in Methotrexate

dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391

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