Sunitinib N,N-Didesethyl Impurity

Product Description
CAT No.
ALN-S016007
CAS No.
1217216-61-9
Mol. F.
C18H19FN4O2 : HCl
Mol. Wt.
342.3 : 36.5
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : N,N-Didesethyl Sunitinib HCl ;Â N-(2-Aminoethyl)-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide HCl ;
Smiles : O=C(C1=C(C)NC(/C=C2C(NC3=C\2C=C(F)C=C3)=O)=C1C)NCCN.Cl
Inchi : InChI=1/C22H27FN4O2.C4H6O5/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28;5-2(4(8)9)1-3(6)7/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28);2,5H,1H2,(H,6,7)(H,8,9)/b17-12-;
Technical Data
Reference
Physicochemical characteristics of sunitinib malate and its process-related impurities
Katarzyna Sidoryk 1, Maura Maliu0144ska, Krzysztof Bau0144kowski, Marek Kubiszewski, Marta u0141aszcz, Magdalena Bodziachowska-Panfil, Magdalena Kossykowska, Tomasz Giller, Andrzej Kutner, Krzysztof Wou017aniaknJ Pharm Sci. 2013 Feb;102(2):706-16.
Development and validation of a HPTLC method for analysis of Sunitinib malate
Monireh Hajmalek, Masoumeh Goudarzi , Solmaz Ghaffari,Hossein Attar, Mehrnoosh Ghanbari Mazlaghan – Brazilian Journal of Pharmaceutical Sciences vol. 52, n. 4, oct./dec., 2016
Reverse phase HPLC determination of sunitinib malate using UV detector, its isomerisation study, method development and validation
Mohsen Padervand, Solmaz Ghaffari, Hossein Attar & Mahdieh Mohammad Nejad – Journal of Analytical Chemistry volume 72, pages567–574(2017)
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