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Tacrolimus 21-Carboxylic Acid Impurity

Tacrolimus 21-Carboxylic Acid Impurity

Product Description
CAT No.
ALN-T005010
CAS No.
NA
Mol. F.
C44H71NO13
Mol. Wt.
822.1
Stock
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RFQ
Chemical Name : 2-((2R,3R,5S)-6-((1S,3S,5Z,7R,10S,11R,12S,13E)-7-Allyl-10-hydroxy-14-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methoxy-3,5,11,13-tetramethyl-8-oxo-12-(((S)-piperidine-2-carbonyl)oxy)tetradeca-5,13-dien-1-yl)-2-hydroxy-5-methoxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetic acid
Smiles : OC(C([C@]1(O)OC([C@@H](OC)C[C@@H](C)C/C(C)=C\[C@@H](CC=C)C(C[C@H](O)[C@@H](C)[C@@H](/C(C)=C/[C@@H]2CC[C@@H](O)[C@H](OC)C2)OC([C@@]3([H])NCCCC3)=O)=O)[C@@H](OC)C[C@H]1C)=O)=O
Inchi : InChI=1S/C16H21NO2/c1-2-15(18)17-9-7-12-4-3-11-5-6-14-13(16(11)12)8-10-19-14/h5-6,12H,2-4,7-10H2,1H3,(H,17,18)/t12-/m1/s1

Development and validation of a stability indicating HPLC assay method for tacrolimus in semi-solid dosage form & bulk drug

By Gejage, Santosh; Amin, PurnimanFrom Indo American Journal of Pharmaceutical Research (2018), 8(5), 1097-1106

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