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Tadalafil EP Impurity A

Tadalafil EP Impurity A

Product Description
CAT No.
ALN-T007002
CAS No.
171596-27-3
Mol. F.
C22H19N3O4
Mol. Wt.
389.4
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Chemical Name : (6R,12aS)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione;
Smiles : O=C([C@]1([H])CC2=C([C@](C3=CC=C(OCO4)C4=C3)([H])N15)NC6=C2C=CC=C6)N(C)CC5=O
Inchi : InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
Synonym : cis-Tadalafil ; 6R,12aS diastereomer

Quantification of Genotoxic Impurities in Tadalafil by Simple and Sensitive Gas Chromatography Technique

Ajit AneraonBhushan Patil

Vishal Solse

Chandrakant Patil – Analytical Chemistry Letters Volume 9, 2019 – Issue 4 Pages 518-525

Chiral Separation of Two Pairs of Enantiomers of Tadalafil by High-Performance Liquid Chromatography

Wenhui Gao, Zhefeng Zhang, Zhiwei Li, and Guijian Liang – Journal of Chromatographic Science, Vol. 45, September 2007

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