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Tadalafil EP Impurity E

Tadalafil EP Impurity E

Product Description
CAT No.
ALN-T007006
CAS No.
1978322-99-4
Mol. F.
C22H19N3O6
Mol. Wt.
421.4
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Chemical Name : (6R,12bR)-6-(Benzo[d][1,3]dioxol-5-yl)-6a-hydroxy-2-methyl-2,3,6a,7,12a,12b-hexahydropyrazino[1′,2′:1,5]pyrrolo[3,4-b]quinoline-1,4,12(6H)-trione
Smiles : O=C([C@@]1([H])C(C(C(C=CC=C2)=C2N3)=O)C3(O)[C@](C4=CC=C(OCO5)C5=C4)([H])N16)N(C)CC6=O
Inchi : InChI=1S/C22H19N3O6/c1-24-9-16(26)25-18(21(24)28)17-20(27)23-13-5-3-2-4-12(13)22(17,29)19(25)11-6-7-14-15(8-11)31-10-30-14/h2-8,17-19,29H,9-10H2,1H3,(H,23,27)/t17?,18-,19?,22?/m1/s1
Synonym : Tadalafil Hydroxypiperidone

Quantification of Genotoxic Impurities in Tadalafil by Simple and Sensitive Gas Chromatography Technique

Ajit AneraonBhushan Patil

Vishal Solse

Chandrakant Patil – Analytical Chemistry Letters Volume 9, 2019 – Issue 4 Pages 518-525

Chiral Separation of Two Pairs of Enantiomers of Tadalafil by High-Performance Liquid Chromatography

Wenhui Gao, Zhefeng Zhang, Zhiwei Li, and Guijian Liang – Journal of Chromatographic Science, Vol. 45, September 2007

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