Tadalafil EP Impurity I (Hydrate)

Product Description
CAT No.
ALN-T007044
CAS No.
NA
Mol. F.
C22H19N3O5 : H2O
Mol. Wt.
405.4 : 18.0
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Technical Data
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Product Overview
Chemical Name : (8a′R)-6′-(1,3-benzodioxol-5-yl)-2′-methyl-2′,3′,8′,8a′-tetrahydro-6′H-spiro[indole-3,7′-pyrrolo[1,2-a]pyrazine]-1′,2,4′(1H)-trione hydrate(as per EP)
Smiles : O=C([C@]1([H])N2C([H])(C3=CC(OCO4)=C4C=C3)C5(C(C=CC=C6)=C6NC5=O)C1)N(C)CC2=O.O
Technical Data
Reference
Quantification of Genotoxic Impurities in Tadalafil by Simple and Sensitive Gas Chromatography Technique
Ajit AneraonBhushan Patil
Vishal Solse
Chandrakant Patil – Analytical Chemistry Letters Volume 9, 2019 – Issue 4 Pages 518-525
Chiral Separation of Two Pairs of Enantiomers of Tadalafil by High-Performance Liquid Chromatography
Wenhui Gao, Zhefeng Zhang, Zhiwei Li, and Guijian Liang – Journal of Chromatographic Science, Vol. 45, September 2007
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