Telmisartan N-Nitroso N-Desmethyl Impurity

Product Description
CAT No.
ALN-T006055
CAS No.
NA
Mol. F.
C32H27N5O3
Mol. Wt.
529.6
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Technical Data
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Product Overview
Chemical Name : 4′-((7′-methyl-1-nitroso-2′-propyl-1H,3’H-[2,5′-bibenzo[d]imidazol]-3′-yl)methyl)-[1,1′-biphenyl]-2-carboxylic acid
Smiles : O=NN1C2=CC=CC=C2N=C1C3=CC(N(CC4=CC=C(C5=C(C(O)=O)C=CC=C5)C=C4)C(CCC)=N6)=C6C(C)=C3
Technical Data
Reference
Detection, isolation and characterization of principle synthetic route indicative impurity in telmisartan
V.Srinivasan, H.Sivaramakrishnan, B.KarthikeyannArabian Journal of Chemistry Volume 9, Supplement 2, November 2016, Pages S1516-S1522
Quality-by-design approach for the development of telmisartan potassium tablets
Ga-Hui Oh, Jin-Hyun Park, Hye-Won Shin, Joo-Eun Kim, Young-Joon Park – Drug Dev Ind Pharm. 2018 May;44(5):837-848.
An Efficient and Impurity-Free Process for Telmisartan:\u2009 An Antihypertensive Drug
Kikkuru Srirami Reddy, Neti Srinivasan, Chinta Raveendra Reddy, Naveenkumar Kolla, Yerremilli Anjaneyulu, Sundaram Venkatraman, Apurba Bhattacharya, and Vijayavitthal T. Mathad – Org. Process Res. Dev. 2007, 11, 1, 81–85
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