Vildagliptin Impurity 4

Product Description
CAT No.
ALN-V008022
CAS No.
1032564-18-3
Mol. F.
C12H19NO3
Mol. Wt.
225.3
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : ((1r,3s,5R,7S)-3-Hydroxyadamantan-1-yl)glycine
Smiles : O=C(O)CN[C@@]12CC3C[C@](O)(C[C@H](C3)C2)C1
Inchi : InChI=1S/C17H26N2O4.C2HF3O2/c20-14(19-3-1-2-13(19)15(21)22)9-18-16-5-11-4-12(6-16)8-17(23,7-11)10-16;3-2(4,5)1(6)7/h11-13,18,23H,1-10H2,(H,21,22);(H,6,7)/t11-,12?,13?,16+,17-;/m1./s1
Technical Data
Reference
Identification, isolation and characterization of potential process-related impurity and its degradation product in vildagliptin
Neeraj Kumar, Subba Rao Devineni, Gurmeet Singh, A.Kadirappa, Shailendra Kumar, Dubey, Pramod KumarnJournal of Pharmaceutical and Biomedical Analysis Volume 119, 5 February 2016, Pages 114-121
Development and validation of a cyclodextrinu2010modified capillary electrophoresis method for the enantiomeric separation of vildagliptin enantiomers
Adrienn Kazsoki\xa0 Ida Fej?s\xa0 Tamás Sohajda\xa0 Wei Zhou\xa0 Wenhui Hu\xa0 Lajos Szente\xa0 Szabolcs Béni – Electrophoresis Volume37, Issue10 May 2016 Pages 1318-1325
New forced degradation products of vildagliptin: Identification and structural elucidation using LC-MS, with proposed formation mechanisms
Sharif Arar,Enas Al-Qudah,Muhammad Alzweiri &Kamal Sweidan – Journal of Liquid Chromatography & Related Technologies\xa0 Volume 43, 2020 – Issue 15-16 Pages 633-644
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