Vildagliptin Impurity 34

Product Description
CAT No.
ALN-V008069
CAS No.
1803168-09-3
Mol. F.
C7H8Cl2N2O
Mol. Wt.
207.1
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : (S)-1-(2,2-Dichloroacetyl)pyrrolidine-2-carbonitrile
Smiles : N#C[C@H]1N(C(C(Cl)Cl)=O)CCC1
Inchi : InChI=1S/C8H11ClN2O3/c9-4-7(13)11-3-1-2-6(11)8(14)10-5-12/h5-6H,1-4H2,(H,10,12,14)/t6-/m0/s1
Technical Data
Reference
Identification, isolation and characterization of potential process-related impurity and its degradation product in vildagliptin
Neeraj Kumar, Subba Rao Devineni, Gurmeet Singh, A.Kadirappa, Shailendra Kumar, Dubey, Pramod KumarnJournal of Pharmaceutical and Biomedical Analysis Volume 119, 5 February 2016, Pages 114-121
Development and validation of a cyclodextrinu2010modified capillary electrophoresis method for the enantiomeric separation of vildagliptin enantiomers
Adrienn Kazsoki\xa0 Ida Fej?s\xa0 Tamás Sohajda\xa0 Wei Zhou\xa0 Wenhui Hu\xa0 Lajos Szente\xa0 Szabolcs Béni – Electrophoresis Volume37, Issue10 May 2016 Pages 1318-1325
New forced degradation products of vildagliptin: Identification and structural elucidation using LC-MS, with proposed formation mechanisms
Sharif Arar,Enas Al-Qudah,Muhammad Alzweiri &Kamal Sweidan – Journal of Liquid Chromatography & Related Technologies\xa0 Volume 43, 2020 – Issue 15-16 Pages 633-644
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