Apixaban Impurity 66

Product Description
CAT No.
ALN-A062088
CAS No.
NA
Mol. F.
C16H18N2O3
Mol. Wt.
286.3
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Technical Data
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Product Overview
Chemical Name : (2Z,4Z)-5-((4-(2-Oxopiperidin-1-yl)phenyl)amino)penta-2,4-dienoic acid
Smiles : O=C(O)/C=C\C=C/NC1=CC=C(N2C(CCCC2)=O)C=C1
Inchi : InChI=1S/C16H16N2O2/c19-15-5-1-3-11-17(15)13-7-9-14(10-8-13)18-12-4-2-6-16(18)20/h1,3,5,7-11H,2,4,6,12H2
Technical Data
Reference
Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmDnClinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma – Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
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