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Bosentan Impurity 6

Bosentan Impurity 6

Product Description
CAT No.
ALN-B017017
CAS No.
NA
Mol. F.
C15H13N5O3
Mol. Wt.
311.3
Stock
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Chemical Name : 6-Amino-5-(2-methoxyphenoxy)-[2,2′-bipyrimidin]-4-ol
Smiles : NC1=C(OC2=CC=CC=C2OC)C(O)=NC(C3=NC=CC=N3)=N1
Inchi : InChI=1S/C15H14O3/c1-9(16)11-4-6-13-12(8-11)5-7-14(18-3)15(13)10(2)17/h4-8H,1-3H3

Research and Development of a Second-Generation Process for Bosentan, an Endothelin Receptor Antagonist

Peter J. Harrington, Hiralal N. Khatri, Brad S. DeHoff, Martin R. Guinn, Mark A. Boehler, and Karl A. GlasernOrganic Process Research & Development 2002, 6, 120u2212124

Stability-Indicating Gradient RP-LC Method for the Determination of Process and Degradation Impurities in Bosentan Monohydrate: An Endothelin Receptor Antagonist

Sanjay A. Jadhav,1 Shashikant B. Landge,1 Sonali L. Jadhav,1 Navanath C. Niphade,1 Saroj R. Bembalkar,2 and Vijayavitthal T. Mathad1 – E-Hindawi Access to Research Chromatography Research International Volume 2011, Article ID 929876, 9 pages

Development and validation of a stability indicating analytical method for the related substances of Bosentan drug substance by HPLC

Mubeen Ahmad Khan, Sukumar Sinha, Mangesh Todkar, Vikas Parashar, K. Swamy Reddy – Am. J. Sci. Ind. Res., 2012, 3(2): 69-80

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