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Diltiazem EP Impurity D

Diltiazem EP Impurity D

Product Description
CAT No.
ALN-D029005
CAS No.
130606-60-9
Mol. F.
C21H24N2O4S : HCl
Mol. Wt.
400.5 : 36.5
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RFQ
Chemical Name : (2S,3S)-5-[2-(Methylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl ;
Smiles : CC(O[C@@H]1[C@H](C2=CC=C(OC)C=C2)SC3=CC=CC=C3N(CCNC)C1=O)=O.Cl
Inchi : InChI=1S/C21H24N2O4S.ClH/c1-14(24)27-19-20(15-8-10-16(25)11-9-15)28-18-7-5-4-6-17(18)23(21(19)26)13-12-22(2)3;/h4-11,19-20,25H,12-13H2,1-3H3;1H/t19-,20+;/m1./s1
Synonym : N-Desmethyl Diltiazem Hydrochloride ;

Identification of Diltiazem Impurities/Artifacts during the Analyses of Illicit Cocaine Exhibits Containing Diltiazem

John F. Casale,1,* Pauline M. Orlando,2 Valerie L. Colley,1 and Patrick A. HaysnMicrogram Journal, Volume 6, Numbers 3-4 (July – December, 2008)

Validated gradient stability indicating HPLC method for determining Diltiazem Hydrochloride and related substances in bulk drug and novel tablet formulation

Pauline M. Orlando,2 Valerie L. Colley,1 and Patrick A. Hays – Microgram Journal, Volume 6, Numbers 3-4 (July – December, 2008)

Analytical Characterization of two new related impurities of Diltiazem by High Resolution Mass spectrometry and NMR techniques

Vivekanand A. ChatpalliwarPawan K. PorwalNeeraj Upmanyu – Journal of Pharmaceutical Analysis Volume 2, Issue 3, June 2012, Pages 226-237

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