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Duloxetine R-Hydroxy Impurity

Duloxetine R-Hydroxy Impurity

Product Description
CAT No.
ALN-D001034
CAS No.
132335-49-0
Mol. F.
C9H15NOS
Mol. Wt.
185.3
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RFQ
Chemical Name : (R)-3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol
Smiles : O[C@@H](C1=CC=CS1)CCN(C)C
Inchi : InChI=1S/C20H24F2O5/c1-17-5-3-10(23)7-13(17)14(21)8-12-11-4-6-19(27,16(25)26)18(11,2)9-15(24)20(12,17)22/h3,5,7,11-12,14-15,24,27H,4,6,8-9H2,1-2H3,(H,25,26)/t11-,12-,14-,15-,17-,18-,19-,20-/m0/s1

Characterization of impurities formed by interaction of duloxetine HCl with enteric polymers hydroxypropyl methylcellulose acetate succinate and hydroxypropyl methylcellulose phthalate

P J Jansen 1, P L Oren, C A Kemp, S R Maple, S W BaertschinJ Pharm Sci. 1998 Jan;87(1):81-5.

Analysis of Duloxetine Hydrochloride and Its Related Compounds in Pharmaceutical Dosage Forms and In Vitro Dissolution Studies by Stability Indicating UPLC

Dantu Durga Rao1,

Development and validation of a stability indicating rp-lc method for the estimation of process related impurities and degradation products of duloxetine hydrochloride and phthalic acid in duloxetine hydrochloride delayed release capsules

, Shakil S. Sait1, A. Malleswara Reddy1, Dinesh Chakole1, Y. Ramakoti Reddy2, and K. Mukkanti – Journal of Chromatographic Science, Vol. 48, November/December 2010

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