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Oxo-Enzalutamide

Oxo-Enzalutamide

Product Description
CAT No.
ALN-E015011
CAS No.
1242137-18-3
Mol. F.
C21H16F4N4O3
Mol. Wt.
448.4
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RFQ
Chemical Name : 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide;
Smiles : CC(N(C1=CC(F)=C(C(NC)=O)C=C1)C2=O)(C)C(N2C3=CC(C(F)(F)F)=C(C#N)C=C3)=O

Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method

Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai OuyangnJournal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification

, Pingkai Ouyang – Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Quantitative Study of\xa0Impurities in\xa0Enzalutamide and\xa0Identification, Isolation, Characterization of\xa0Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and\xa0NMR Analyses

Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari – Cryst. Growth Des. 2018, 18, 7, 3774–3780

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