Enzalutamide Impurity 28

Product Description
CAT No.
ALN-E015046
CAS No.
NA
Mol. F.
C18H10F6N4O
Mol. Wt.
412.3
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Technical Data
Reference
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Product Overview
Chemical Name : 1,3-Bis(4-cyano-3-(trifluoromethyl)phenyl)-1-methylurea
Smiles : FC(C1=CC(NC(N(C2=CC=C(C#N)C(C(F)(F)F)=C2)C)=O)=CC=C1C#N)(F)F
Inchi : InChI=1S/C9H5F3N2OS/c10-9(11,12)7-3-5(14-4-16)1-2-6(7)8(13)15/h1-3H,(H2,13,15)
Technical Data
Reference
Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method
Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai OuyangnJournal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443
Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification
, Pingkai Ouyang – Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443
Quantitative Study of\xa0Impurities in\xa0Enzalutamide and\xa0Identification, Isolation, Characterization of\xa0Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and\xa0NMR Analyses
Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari – Cryst. Growth Des. 2018, 18, 7, 3774–3780
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