Enzalutamide Impurity 34

Product Description
CAT No.
ALN-E015051
CAS No.
654-70-6
Mol. F.
C8H5F3N2
Mol. Wt.
186.1
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Technical Data
Reference
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Product Overview
Chemical Name : 4-Amino-2-(trifluoromethyl)benzonitrile
Smiles : N#CC1=CC=C(N)C=C1C(F)(F)F
Inchi : InChI=1S/C15H11F4NO/c1-2-8-3-4-12(9(5-8)7-21)20-15-13(18)10(16)6-11(17)14(15)19/h3-7,20H,2H2,1H3
Technical Data
Reference
Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method
Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai OuyangnJournal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443
Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification
, Pingkai Ouyang – Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443
Quantitative Study of\xa0Impurities in\xa0Enzalutamide and\xa0Identification, Isolation, Characterization of\xa0Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and\xa0NMR Analyses
Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari – Cryst. Growth Des. 2018, 18, 7, 3774–3780
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