Erlotinib Chloro Impurity

Product Description
CAT No.
ALN-E018009
CAS No.
183322-18-1
Mol. F.
C14H17ClN2O4
Mol. Wt.
312.8
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline
Smiles : ClC1=NC=NC2=CC(OCCOC)=C(OCCOC)C=C12
Inchi : InChI=1S/C20H19N3O4/c1-2-14-4-3-5-15(10-14)23-20-16-11-18(26-8-6-24)19(27-9-7-25)12-17(16)21-13-22-20/h1,3-5,10-13,24-25H,6-9H2,(H,21,22,23)
Technical Data
Reference
Erlotinib in combination with capecitabine and docetaxel in patients with metastatic breast cancer: A dose-escalation study
Chris Twelvesa, Joseu00b4 M. Trigob , Rob Jonesc , Flavio De Rosad , Ashok Rakhite , Scott Fettnere , Tonya Wrightc , Joseu00b4 BaselganEuropean journal of cancer 44 (2008) 419 u2013 426
Development and validation of a stability indicating HPLC method for the quantification of impurities in Erlotinib hydrochloride dosage forms
BabuC1, Narasimha\xa0 RaoK.L1,\xa0 DevannaN1, Suresh Reddy\xa0 K.V.N – Solubility Measurement and Correlation of Two Erlotinib Hydrochloride Polymorphs in Alcohols and Ketones from 273.15 to 323.15 K
Jinghuan Zhai, Junrui Zhao, Zhenzhen Chen, Changwei Xiao, Xijian Liu, Lijuan Zhang, and Jie Lu
J. Chem. Eng. Data 2017, 62, 1, 516–524 – Separation and Determination of Process-Related Impurities of Erlotinib Using Reverse-Phase HPLC with a Photo-Diode Array Detector
RFQ