Erlotinib Impurity 1

CAT No.

ALN-E018017

CAS No.

1710372-46-5

Mol. F.

C14H16Cl2N2O4

Mol. Wt.

347.2

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Product Overview

Technical Data

Reference

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Product Overview

Chemical Name : 2,4-Dichloro-6,7-bis(2-methoxyethoxy)quinazoline

Smiles : COCCOC1=C(OCCOC)C=C2C(N=C(Cl)N=C2Cl)=C1

Inchi : InChI=1S/C22H25N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h4-7,12-15H,1,8-11H2,2-3H3,(H,23,24,25)

Technical Data

Reference

Chris Twelvesa, Joseu00b4 M. Trigob , Rob Jonesc , Flavio De Rosad , Ashok Rakhite , Scott Fettnere , Tonya Wrightc , Joseu00b4 BaselganEuropean journal of cancer 44 (2008) 419 u2013 426

BabuC1, Narasimha\xa0 RaoK.L1,\xa0 DevannaN1, Suresh Reddy\xa0 K.V.N – Solubility Measurement and Correlation of Two Erlotinib Hydrochloride Polymorphs in Alcohols and Ketones from 273.15 to 323.15 K

J. Chem. Eng. Data 2017, 62, 1, 516–524 – Separation and Determination of Process-Related Impurities of Erlotinib Using Reverse-Phase HPLC with a Photo-Diode Array Detector

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