Fluticasone Propionate EP Impurity H

CAT No.

ALN-F016009

CAS No.

201812-64-8

Mol. F.

C48H58F4O10S2

Mol. Wt.

935.1

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Product Overview

Technical Data

Reference

RFQ

Product Overview

Chemical Name : 17,17â€²-(Disulphanediyldicarbonyl)bis(6Î±,9-difluoro-11Î²-hydroxy-16Î±-methyl-3-oxoandrosta-1,4-dien-17Î±-yl) dipropanoate ;

Smiles : C[C@@]12[C@@](OC(CC)=O)(C(SSC([C@]([C@@]3(C)C[C@@H]([C@]([C@](C4=CC5=O)(C=C5)C)([C@]6(C[C@@H]4F)[H])F)O)([C@@H](C[C@]36[H])C)OC(CC)=O)=O)=O)[C@H](C)C[C@@]1([H])[C@]7([H])C[C@H](F)C8=CC(C=C[C@]8(C)[C@@]7(F)[C@@H](O)C2)=O

Inchi : InChI=1S/C43H51F5O8S/c1-20-11-24-26-15-30(45)28-13-22(49)7-9-36(28,3)40(26,47)32(51)17-38(24,5)42(20,55)34(53)56-43(35(54)57-19-44)21(2)12-25-27-16-31(46)29-14-23(50)8-10-37(29,4)41(27,48)33(52)18-39(25,43)6/h7-10,13-14,20-21,24-27,30-33,51-52,55H,11-12,15-19H2,1-6H3/t20-,21-,24+,25+,26+,27+,30+,31+,32+,33+,36+,37+,38+,39+,40+,41+,42+,43+/m1/s1

Synonym : Fluticasone Disulphane Impurity ; Desfluoromethyl Fluticasone Propionate Disulfide ;

Technical Data

Reference

Nisha Mistry a , Ismail M. Ismail b , Marco S. Smith c , Jeremy K. Nicholson d , John C. LindonnJournal of Pharmaceutical and Biomedical Analysis 16 (1997) 697u2013705