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Fluticasone Furoate 11-Keto Impurity

Fluticasone Furoate 11-Keto Impurity

Product Description
CAT No.
ALN-F016053
CAS No.
397864-56-1
Mol. F.
C27H27F3O6S
Mol. Wt.
536.6
Stock
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RFQ
Chemical Name : (6S,8S,9R,10S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-10,13,16-trimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate
Smiles : C[C@@]1(C2)[C@](C(SCF)=O)(OC(C3=CC=CO3)=O)[C@H](C)C[C@@]1([H])[C@]4([H])C[C@H](F)C5=CC(C=C[C@]5(C)[C@@]4(F)C2=O)=O
Inchi : InChI=1S/C15H14N2O6/c1-7-11(14(18)19)13(12(15(20)21)8(2)16-7)9-4-3-5-10(6-9)17(22)23/h3-6,13,16H,1-2H3,(H,18,19)(H,20,21)

Characterisation of impurities in bulk drug batches of fluticasone propionate using directly coupled HPLCu2013NMR spectroscopy and HPLCu2013MS

Nisha Mistry a , Ismail M. Ismail b , Marco S. Smith c , Jeremy K. Nicholson d , John C. LindonnJournal of Pharmaceutical and Biomedical Analysis 16 (1997) 697u2013705

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