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Furosemide EP Impurity B

Furosemide EP Impurity B

Product Description
CAT No.
ALN-F032003
CAS No.
2736-23-4
Mol. F.
C7H5Cl2NO4S
Mol. Wt.
270.1
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RFQ
Chemical Name : 2,4-Dichloro-5-sulfamoylbenzoic acid
Smiles : O=C(O)C1=CC(S(=O)(N)=O)=C(Cl)C=C1Cl
Inchi : InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)11(21(14,18)19)4-8(9)12(16)17/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)

A New Way of Stabilization of Furosemide upon Cryogenic Grinding by Using Acylated Saccharides Matrices. The Role of Hydrogen Bonds in Decomposition Mechanism

E. Kaminska,*,u2020 K. Adrjanowicz,u2021,u00a7 K. Kaminski,u00a7,u2225 P. Wlodarczyk,u22a5 L. Hawelek,u00a7,u22a5 K. Kolodziejczyk,u00a7 M. Tarnacka,u00a7 D. Zakowiecki,# I. Kaczmarczyk-Sedlak,u2020 J. Pilch,u2207 and M. PaluchnMol. Pharmaceutics 2013, 10, 5, 1824u20131835

Effect of Cryogrinding on Chemical Stability of the Sparingly Water-Soluble Drug Furosemide

,† K. Adrjanowicz,‡,§ K. Kaminski,§,∥ P. Wlodarczyk,⊥ L. Hawelek,§,⊥ K. Kolodziejczyk,§ M. Tarnacka,§ D. Zakowiecki,# I. Kaczmarczyk-Sedlak,† J. Pilch,∇ and M. Paluch – Mol. Pharmaceutics 2013, 10, 5, 1824–1835

Implementation of design of experiments for optimization of forced degradation conditions and development of a stability-indicating method for furosemide

Karolina Adrjanowicz, Kamil Kaminski, Katarzyna Grzybowska, Lukasz Hawelek, Marian Paluch, Irena Gruszka, Daniel Zakowiecki, Wieslaw Sawicki, Przemyslaw Lepek, Wojciech Kamysz & Lukasz Guzik – Pharmaceutical Research volume 28, pages3220–3236(2011)

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