Ivabradine Impurity 17

Product Description
CAT No.
ALN-I014044
CAS No.
NA
Mol. F.
C27H36N2O6 : HCl
Mol. Wt.
484.6 : 36.5
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-1-hydroxy-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride
Smiles : COC1=C(OC)C=C(CCN(CCCN(C)C[C@@H]2C(C=C(OC)C(OC)=C3)=C3C2)C(C4O)=O)C4=C1.Cl
Inchi : InChI=1S/C31H44N2O5.ClH/c1-7-10-24-26-19-30(38-6)27(35-3)16-21(26)11-14-33(31(24)34)13-9-12-32(8-2)20-23-15-22-17-28(36-4)29(37-5)18-25(22)23;/h16-19,23-24H,7-15,20H2,1-6H3;1H/t23-,24?;/m1./s1
Technical Data
Reference
Forced Degradation Studies of Ivabradine and In Silico Toxicology Predictions for Its New Designated Impurities
Piotr Pikul,1 Marzena Jamru00f3giewicz,1,* Joanna Nowakowska,1 Weronika Hewelt-Belka,2,3 and Krzesimir CiuranFront Pharmacol. 2016; 7: 117.
Simultaneous determination of chiral and achiral impurities of ivabradine on a cellulose tris(3-chloro-4-methylphenylcarbamate) chiral column using polar organic mode
Joanna Nowakowska,1 Weronika Hewelt-Belka,2,3 and Krzesimir Ciura – Front Pharmacol. 2016; 7: 117.
Characterization of degradation products of Ivabradine by LC-HR-MS/MS: a typical case of exhibition of different degradation behaviour in HCl and H2SO4 acid hydrolysis
ElekFerenczabBélaKovácsabFranciscBodaaMohammadhassanForoughbakhshfasaeicÉva KatalinKelemenbGerg?TóthcZoltán-IstvánSzabó – Journal of Pharmaceutical and Biomedical Analysis Volume 177, 5 January 2020, 112851
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