Ivabradine Impurity 51

Product Description
CAT No.
ALN-I014083
CAS No.
20925-64-8
Mol. F.
C12H15NO3
Mol. Wt.
221.3
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Smiles : O=C1NCCC2=CC(OC)=C(OC)C=C2C1
Inchi : InChI=1S/C19H31N7O6.C2HF3O2/c1-9(2)12(20)16(28)23-13(10(3)4)18(30)31-6-11(5-27)32-8-26-7-22-14-15(26)24-19(21)25-17(14)29;3-2(4,5)1(6)7/h7,9-13,27H,5-6,8,20H2,1-4H3,(H,23,28)(H3,21,24,25,29);(H,6,7)/t11?,12-,13-;/m0./s1
Technical Data
Reference
Forced Degradation Studies of Ivabradine and In Silico Toxicology Predictions for Its New Designated Impurities
Piotr Pikul,1 Marzena Jamru00f3giewicz,1,* Joanna Nowakowska,1 Weronika Hewelt-Belka,2,3 and Krzesimir CiuranFront Pharmacol. 2016; 7: 117.
Simultaneous determination of chiral and achiral impurities of ivabradine on a cellulose tris(3-chloro-4-methylphenylcarbamate) chiral column using polar organic mode
Joanna Nowakowska,1 Weronika Hewelt-Belka,2,3 and Krzesimir Ciura – Front Pharmacol. 2016; 7: 117.
Characterization of degradation products of Ivabradine by LC-HR-MS/MS: a typical case of exhibition of different degradation behaviour in HCl and H2SO4 acid hydrolysis
ElekFerenczabBélaKovácsabFranciscBodaaMohammadhassanForoughbakhshfasaeicÉva KatalinKelemenbGerg?TóthcZoltán-IstvánSzabó – Journal of Pharmaceutical and Biomedical Analysis Volume 177, 5 January 2020, 112851
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