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Levofloxacin EP Impurity A

Levofloxacin EP Impurity A

Product Description
CAT No.
ALN-L020008
CAS No.
100986-86-5
Mol. F.
C18H20FN3O4
Mol. Wt.
361.4
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Chemical Name : (R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7Hpyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
Smiles : O=C(C(C1=O)=CN2[C@H](C)COC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O
Inchi : InChI=1S/C28H31NO10/c1-4-17(30)28(36)9-13-20(16(10-28)39-18-8-14(29)23(31)11(2)38-18)27(35)22-21(25(13)33)24(32)12-6-5-7-15(37-3)19(12)26(22)34/h5-7,11,14,16,18,23,31,33,35-36H,4,8-10,29H2,1-3H3/t11-,14-,16-,18-,23+,28-/m0/s1
Synonym : (R)-(+)-Ofloxacin ; D-Ofloxacin ; Ofloxacin R-Isomer ; Levofloxacin D-Isomer

In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin

Qingfen Zhu1,2, Tao Li2 , Jun Li2 , Ming Guo2 , Weijian Wang2 , and Xiumei ZhangnToxicology Mechanisms and Methods, 2012; 22(3): 225u2013230

Identification, Isolation and Characterization of New Process-related Impurities in Levofloxacin

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An integrated approach for detection and characterization of the trace impurities in levofloxacin using liquid chromatography– tandem mass spectrometry

, Leena Gupta, Brajesh Sharma, Prashant Patil, Dattatray Govare – Der Pharma Chemica, 2017, 9(12):7-13

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