Lopinavir EP Impurity C
 
		Product Description
CAT No.
				
									ALN-L008004								
				CAS No.
				
									NA								
				Mol. F.
				
									C36H52N6O5								
				Mol. Wt.
				
									648.8								
				Stock
				
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										Technical Data
						
											
										
							
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							Product Overview
			
						
									Chemical Name : (2R)-N-[(1S,2S,4S)-1-Benzyl-2-hydroxy-4-[[(2S)-3-methyl2-[2-oxotetrahydro pyrimidin-1(2H)-yl]butanoyl]amino]5-phenylpentyl]-3-methyl-2-[2-oxotetra hydropyrimidin1(2H)-yl]butanamide (as per EP);
 (2S,2′S)-N,N′-[(2S,3S,5S)-3-Hydroxy-1,6-diphenylhexane-2,5-diyl]bis{3-methyl-2-[2-oxotetrahydropyrimidin-1(2H)-yl]butanamide} (as per USP)								
				
									Smiles : CC(C)[C@H](N1CCCNC1=O)C(N[C@H](C[C@H](O)[C@@H](NC([C@H](N2CCCNC2=O)C(C)C)=O)CC3=CC=CC=C3)CC4=CC=CC=C4)=O								
				
									Inchi : InChI=1S/C27H38N4O3/c1-19(2)25(31-15-9-14-29-27(31)34)26(33)30-22(16-20-10-5-3-6-11-20)18-24(32)23(28)17-21-12-7-4-8-13-21/h3-8,10-13,19,22-25,32H,9,14-18,28H2,1-2H3,(H,29,34)(H,30,33)/t22-,23-,24-,25-/m0/s1								
				
									Synonym : Lopinavir Divalinate (USP)								
				
							
							
							Technical Data
			
						
							
							
							Reference
			
						Stability indicative and cost effective creation and validation of analytical method of Lopinavir and Rilpivirine by high performance liquid chromatography
									By Srinivas, L.; Jain, NeelunFrom International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 786-792								
				Analytical methods development & validation for simultaneous estimation of lopinavir & ritonavir in pharmaceutical formulation by simultaneous equation method using UV spectrophotometry
									By Jadhav, Sarika R.; Alhat, Hemant P.; Joshi, Suhas – From International Research Journal of Pharmacy (2018), 9(8), 57-62 								
				Development and validation of forced degradation studies of lopinavir using RP-HPLC and characterization of degradants by LC-MS/MS
									By Bhavyasri, Khagga; Balaram, V. Murali; Nageswarao, R.; Rambabu, D.; Ajitha, M. – From International Journal of Chemical Sciences (2015), 13(1), 551-562								
				
							
							
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