Losartan EP Impurity M

Product Description
CAT No.
ALN-L028014
CAS No.
230971-72-9
Mol. F.
C44H44Cl2N12O
Mol. Wt.
827.8
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : [2-Butyl-1-[[2′-[2-[[2-butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methyl]-2H-tetrazol-5-yl]biphenyl-4-yl]methyl]-4-chloro-1H-imidazol-5-yl]methanol (as per EP)
Smiles : OCC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NN(CC5=C(Cl)N=C(CCCC)N5CC6=CC=C(C7=CC=CC=C7C8=NNN=N8)C=C6)N=N4)C=C2
Inchi : InChI=1S/C44H44Cl2N12O/c1-3-5-15-39-47-41(45)37(56(39)25-29-17-21-31(22-18-29)33-11-7-9-13-35(33)43-49-52-53-50-43)27-58-44(51-54-55-58)36-14-10-8-12-34(36)32-23-19-30(20-24-32)26-57-38(28-59)42(46)48-40(57)16-6-4-2/h7-14,17-24,59H,3-6,15-16,25-28H2,1-2H3,(H,49,50,52,53)
Synonym : Losartan USP Related Compound E ; Losartan N2-Dimer ; N2-Losartanyl Losartan
Technical Data
Reference
Development and validation of a stability-indicating HPLC method for the simultaneous determination of Losartan potassium, hydrochlorothiazide, and their degradation products
Deanne L. Hertzog a,*, Jennifer Finnegan McCafferty b , Xueguang Fang b , R. Jeffrey Tyrrell c , Robert A. ReednJournal of Pharmaceutical and Biomedical Analysis 30 (2002) 747u2013760
An Efficient, Commercially Viable, and Safe Process for Preparation of Losartan Potassium, an Angiotensin II Receptor Antagonist
, Jennifer Finnegan McCafferty b , Xueguang Fang b , R. Jeffrey Tyrrell c , Robert A. Reed – Journal of Pharmaceutical and Biomedical Analysis 30 (2002) 747–760
Suri Babu Madasu,†,‡ N. A. Vekariya,
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