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Losartan Impurity 14

Losartan Impurity 14

Product Description
CAT No.
ALN-L028049
CAS No.
178554-16-0
Mol. F.
C25H26N6O3
Mol. Wt.
458.5
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Chemical Name : 2-(1-((2′-(1H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-butyl-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)acetic acid
Smiles : O=C1N(C(CCCC)=NC(C)=C1CC(O)=O)CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2
Inchi : InChI=1S/C16H26N2O5S/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23)/b12-6+/t10-,11+/m1/s1

Development and validation of a stability-indicating HPLC method for the simultaneous determination of Losartan potassium, hydrochlorothiazide, and their degradation products

Deanne L. Hertzog a,*, Jennifer Finnegan McCafferty b , Xueguang Fang b , R. Jeffrey Tyrrell c , Robert A. ReednJournal of Pharmaceutical and Biomedical Analysis 30 (2002) 747u2013760

An Efficient, Commercially Viable, and Safe Process for Preparation of Losartan Potassium, an Angiotensin II Receptor Antagonist

, Jennifer Finnegan McCafferty b , Xueguang Fang b , R. Jeffrey Tyrrell c , Robert A. Reed – Journal of Pharmaceutical and Biomedical Analysis 30 (2002) 747–760
Suri Babu Madasu,†,‡ N. A. Vekariya,

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