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Nicardipine Impurity 11

Nicardipine Impurity 11

Product Description
CAT No.
ALN-N004026
CAS No.
NA
Mol. F.
C33H34N4O9
Mol. Wt.
630.7
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RFQ
Chemical Name : 1-(2-(Benzyl(methyl)amino)ethyl) 5-methyl (E)-2-acetyl-4-(1-(((E)-3-nitrobenzylidene)amino)ethylidene)-3-(3-nitrophenyl)pentanedioate
Smiles : O=C(OCCN(CC1=CC=CC=C1)C)C(C(C)=O)C(C2=CC=CC([N+]([O-])=O)=C2)/C(C(OC)=O)=C(\N=C\C3=CC=CC([N+]([O-])=O)=C3)C
Inchi : InChI=1/C33H34N4O9/c1-22(34-20-25-12-8-14-27(18-25)36(41)42)29(32(39)45-4)31(26-13-9-15-28(19-26)37(43)44)30(23(2)38)33(40)46-17-16-35(3)21-24-10-6-5-7-11-24/h5-15,18-20,30-31H,16-17,21H2,1-4H3/b29-22+,34-20-

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS

Sheikha M.Al-Ghannam,Abeer M.Al-OlayannArabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993

Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance

M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain – Pharm Res. 1992 Nov;9(11):1518-20.

Chromatographic purity and assay of nicardipine by HPLC

C. V. Fernández\xa0 D. F. Mira\xa0 G. I. Luque – Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849

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