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Paroxetine EP Impurity I

Paroxetine EP Impurity I

Product Description
CAT No.
ALN-P012010
CAS No.
220548-73-2
Mol. F.
C12H16FNO : HCl
Mol. Wt.
209.3 : 36.5
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RFQ
Chemical Name : [(3S,4R)-4-(4-fluorophenyl)piperidin-3-yl]methanol hydrochloride
Smiles : OC[C@@H]1CNCC[C@H]1C2=CC=C(F)C=C2.Cl
Inchi : InChI=1S/C19H22FNO.ClH/c20-18-8-6-16(7-9-18)19-10-11-21(13-17(19)14-22)12-15-4-2-1-3-5-15;/h1-9,17,19,22H,10-14H2;1H/t17-,19-;/m0./s1
Synonym : Paroxetine Hydrochloride Piperidinemethanol Analog (USP)

Development, validation and transfer into a factory environment of a liquid chromatography tandem mass spectrometry assay for the highly neurotoxic impurity FMTP (4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine) in paroxetine active pharmaceutical ingredient (API)

Phil J.Borman, Marion J.Chatfield, Elizabeth L.Crowley, ChristineEckers, David P.Elder, Scott W.Francey, Alice M.-F.Laures, Jean-ClaudeWolffnJournal of Pharmaceutical and Biomedical Analysis Volume 48, Issue 4, 1 December 2008, Pages 1082-1089

An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form

M. Fátima Pina, Min Zhao, João F. Pinto, João J. Sousa, Christopher S. Frampton, Victor Diaz, Osama Suleiman, László Fábián, and Duncan Q. M. Craig – Cryst. Growth Des. 2014, 14, 8, 3774–3782

Determination of residual solvents in paroxetine by headspace gas chromatography

abdul rahaman sk, padmavathi sakinala, khaleel n, harekrishna roy – Asian J Pharm Clin Res, Vol 12, Issue 6, 2019, 150-155

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