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Paroxetine Hydrochloride Hemihydrate EP Impurity B

Paroxetine Hydrochloride Hemihydrate EP Impurity B

Product Description
CAT No.
ALN-P012012
CAS No.
127017-74-7
Mol. F.
C20H23NO4 : HCl
Mol. Wt.
341.4 : 36.5
Stock
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RFQ
Chemical Name : (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-methoxyphenyl)piperidine hydrochloride
Smiles : COC1=CC=C([C@H]2[C@H](COC3=CC=C(OCO4)C4=C3)CNCC2)C=C1.Cl
Inchi : InChI=1S/C2H2O4/c3-1(4)2(5)6/h(H,3,4)(H,5,6)

Development, validation and transfer into a factory environment of a liquid chromatography tandem mass spectrometry assay for the highly neurotoxic impurity FMTP (4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine) in paroxetine active pharmaceutical ingredient (API)

Phil J.Borman, Marion J.Chatfield, Elizabeth L.Crowley, ChristineEckers, David P.Elder, Scott W.Francey, Alice M.-F.Laures, Jean-ClaudeWolffnJournal of Pharmaceutical and Biomedical Analysis Volume 48, Issue 4, 1 December 2008, Pages 1082-1089

An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form

M. Fátima Pina, Min Zhao, João F. Pinto, João J. Sousa, Christopher S. Frampton, Victor Diaz, Osama Suleiman, László Fábián, and Duncan Q. M. Craig – Cryst. Growth Des. 2014, 14, 8, 3774–3782

Determination of residual solvents in paroxetine by headspace gas chromatography

abdul rahaman sk, padmavathi sakinala, khaleel n, harekrishna roy – Asian J Pharm Clin Res, Vol 12, Issue 6, 2019, 150-155

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