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Paroxetine Impurity 1

Paroxetine Impurity 1

Product Description
CAT No.
ALN-P012025
CAS No.
274-09-9
Mol. F.
C7H6O2
Mol. Wt.
122.1
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Chemical Name : Benzo[d][1,3]dioxole
Smiles : C1(C=CC=C2)=C2OCO1
Inchi : InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33-,34-,36-,37+,38+,39+,40-,42-,43+,44-,46-,47+,51-/m1/s1

Development, validation and transfer into a factory environment of a liquid chromatography tandem mass spectrometry assay for the highly neurotoxic impurity FMTP (4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine) in paroxetine active pharmaceutical ingredient (API)

Phil J.Borman, Marion J.Chatfield, Elizabeth L.Crowley, ChristineEckers, David P.Elder, Scott W.Francey, Alice M.-F.Laures, Jean-ClaudeWolffnJournal of Pharmaceutical and Biomedical Analysis Volume 48, Issue 4, 1 December 2008, Pages 1082-1089

An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form

M. Fátima Pina, Min Zhao, João F. Pinto, João J. Sousa, Christopher S. Frampton, Victor Diaz, Osama Suleiman, László Fábián, and Duncan Q. M. Craig – Cryst. Growth Des. 2014, 14, 8, 3774–3782

Determination of residual solvents in paroxetine by headspace gas chromatography

abdul rahaman sk, padmavathi sakinala, khaleel n, harekrishna roy – Asian J Pharm Clin Res, Vol 12, Issue 6, 2019, 150-155

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