Paroxetine Hydrochloride Hemihydrate EP Impurity C
 
		Product Description
CAT No.
				
									ALN-P012027								
				CAS No.
				
									NA								
				Mol. F.
				
									C21H25NO4 : HCl								
				Mol. Wt.
				
									355.4 : 36.5								
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							Product Overview
			
						
									Chemical Name : (3S,4R)-3-[[(1,3-benzodioxol-5-yl)oxy]methyl]-4-(4-ethoxyphenyl)piperidine hydrochloride								
				
									Smiles : CCOC1=CC=C([C@H]2[C@H](COC3=CC=C(OCO4)C4=C3)CNCC2)C=C1.Cl								
				
									Inchi : InChI=1S/C8H10N2O3S/c1-7-3-5-8(6-4-7)14(12,13)10(2)9-11/h3-6H,1-2H3								
				
							
							
							Technical Data
			
						
							
							
							Reference
			
						Development, validation and transfer into a factory environment of a liquid chromatography tandem mass spectrometry assay for the highly neurotoxic impurity FMTP (4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine) in paroxetine active pharmaceutical ingredient (API)
									Phil J.Borman, Marion J.Chatfield, Elizabeth L.Crowley, ChristineEckers, David P.Elder, Scott W.Francey, Alice M.-F.Laures, Jean-ClaudeWolffnJournal of Pharmaceutical and Biomedical Analysis Volume 48, Issue 4, 1 December 2008, Pages 1082-1089								
				An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form
									M. Fátima Pina, Min Zhao, João F. Pinto, João J. Sousa, Christopher S. Frampton, Victor Diaz, Osama Suleiman, László Fábián, and Duncan Q. M. Craig – Cryst. Growth Des. 2014, 14, 8, 3774–3782 								
				Determination of residual solvents in paroxetine by headspace gas chromatography
									abdul rahaman sk, padmavathi sakinala, khaleel n, harekrishna roy – Asian J Pharm Clin Res, Vol 12, Issue 6, 2019, 150-155 								
				
							
							
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