Paroxetine Impurity 5

Product Description
CAT No.
ALN-P012033
CAS No.
NA
Mol. F.
C31H40FNO13
Mol. Wt.
653.7
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : (2S,3R,4S,5R,6R)-2-(((2R,3S,4R,5R,6R)-6-((3S,4R)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidin-1-yl)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Smiles : FC(C=C1)=CC=C1[C@@H]([C@H](COC2=CC=C3C(OCO3)=C2)C4)CCN4[C@@H]([C@H](O)[C@H]5O)O[C@H](CO)[C@H]5O[C@H]6[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O6
Technical Data
Reference
Development, validation and transfer into a factory environment of a liquid chromatography tandem mass spectrometry assay for the highly neurotoxic impurity FMTP (4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine) in paroxetine active pharmaceutical ingredient (API)
Phil J.Borman, Marion J.Chatfield, Elizabeth L.Crowley, ChristineEckers, David P.Elder, Scott W.Francey, Alice M.-F.Laures, Jean-ClaudeWolffnJournal of Pharmaceutical and Biomedical Analysis Volume 48, Issue 4, 1 December 2008, Pages 1082-1089
An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form
M. Fátima Pina, Min Zhao, João F. Pinto, João J. Sousa, Christopher S. Frampton, Victor Diaz, Osama Suleiman, László Fábián, and Duncan Q. M. Craig – Cryst. Growth Des. 2014, 14, 8, 3774–3782
Determination of residual solvents in paroxetine by headspace gas chromatography
abdul rahaman sk, padmavathi sakinala, khaleel n, harekrishna roy – Asian J Pharm Clin Res, Vol 12, Issue 6, 2019, 150-155
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