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N-Nitroso paroxetine Impurity

N-Nitroso paroxetine Impurity

Product Description
CAT No.
ALN-P012026
CAS No.
2361294-43-9
Mol. F.
C19H19FN2O4
Mol. Wt.
358.4
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RFQ
Chemical Name : (3S,4R)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-1-nitrosopiperidine
Smiles : O=NN(CC1)C[C@@H](COC2=CC(OCO3)=C3C=C2)[C@@H]1C4=CC=C(F)C=C4
Inchi : InChI=1S/C17H26N2O5/c1-17(2,3)19(18-23)9-12(20)10-24-16-6-4-5-11-7-14(21)15(22)8-13(11)16/h4-6,12,14-15,20-22H,7-10H2,1-3H3/t12?,14-,15+/m1/s1

Development, validation and transfer into a factory environment of a liquid chromatography tandem mass spectrometry assay for the highly neurotoxic impurity FMTP (4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine) in paroxetine active pharmaceutical ingredient (API)

Phil J.Borman, Marion J.Chatfield, Elizabeth L.Crowley, ChristineEckers, David P.Elder, Scott W.Francey, Alice M.-F.Laures, Jean-ClaudeWolffnJournal of Pharmaceutical and Biomedical Analysis Volume 48, Issue 4, 1 December 2008, Pages 1082-1089

An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form

M. Fátima Pina, Min Zhao, João F. Pinto, João J. Sousa, Christopher S. Frampton, Victor Diaz, Osama Suleiman, László Fábián, and Duncan Q. M. Craig – Cryst. Growth Des. 2014, 14, 8, 3774–3782

Determination of residual solvents in paroxetine by headspace gas chromatography

abdul rahaman sk, padmavathi sakinala, khaleel n, harekrishna roy – Asian J Pharm Clin Res, Vol 12, Issue 6, 2019, 150-155

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