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Ribociclib N-Desmethyl Metabolite Free base

Ribociclib N-Desmethyl Metabolite Free base

Product Description
CAT No.
ALN-R035021
CAS No.
1211441-59-6
Mol. F.
C22H28N8O
Mol. Wt.
420.5
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RFQ
Chemical Name : 7-Cyclopentyl-N-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide
Smiles : O=C(C1=CC2=CN=C(NC3=CC=C(N4CCNCC4)C=N3)N=C2N1C5CCCC5)NC
Inchi : InChI=1S/C23H30N8O.H2O4S/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30;1-5(2,3)4/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28);(H2,1,2,3,4)

Quantification of ribociclib in dried blood spots by LC-MS/MS: Method development and clinical validation

By Braal C Louwrens; Lam Mei H; Bos Monique E M M; Mathijssen Ron H J; de Bruijn Peter; Rienks Tineke; van Tilborg Claudia J; Heuts Wendy; Heijns Joan B; Koolen Stijn L WnFrom Journal of pharmaceutical and biomedical analysis (2021), 201, 114118

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