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Abacavir EP Impurity F

Abacavir EP Impurity F

Product Description
CAT No.
ALN-A049007
CAS No.
1443421-68-8
Mol. F.
C18H26N6O
Mol. Wt.
342.4
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RFQ
Chemical Name : 6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(1,1-dimethylethyl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine (as per EP) ; 9-[(1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-enyl]-N6-cyclopropyl-9H-purine-2,6-diamine (as per USP)
Smiles : [H][C@@]1(C=C[C@](COC(C)(C)C)([H])C1)N2C3=NC(N)=NC(NC4CC4)=C3N=C2
Inchi : InChI=1S/C14H20N6O/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21/h7-10,21H,1-6H2,(H3,15,17,18,19)/t8-,10+/m1/s1
Synonym : O-t-Butyl Derivative Abacavir (USP)

Stability indicating RP-HPLC method development and validation for determination of abacavir sulphate in tablet dosage form

By Ithape, Aniket B.; Deshpande, Padmanabh B.; Shelke, PriyankanFrom International Journal of Pharmacy and Pharmaceutical Research (2020), 17(4), 670-680

A new stability indicating method was developed and validated for the simultaneous estimation of Lamivudine and Abacavir in tablet dosage form by RP-HPLC

By Rajamahanti, Santoshi G.; Annapurna, N.; Santosh, T.; Durga, B.; Raziya, S. K. – From Research Journal of Pharmaceutical, Biological and Chemical Sciences (2017), 8(3), 407-421

A validated stability-indicating RP-HPLC method for abacavir sulfate in the presence of degradation products, its process-related impurities and identification of oxidative degradant by LC-MS/MS

By Ragham, Pramod Kumar; Chandrasekhar, Kothapalli B.; Reddy, J. Rudraprasad; Kasturi, Krishna Mohan – From Indo American Journal of Pharmaceutical Research (2015), 5(1), 463-473

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