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Abacavir EP Impurity B

Abacavir EP Impurity B

Product Description
CAT No.
ALN-A049003
CAS No.
1443421-69-9
Mol. F.
C18H21ClN10O
Mol. Wt.
428.9
Stock
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Chemical Name : 6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(2,5-diamino-6-chloropyrimidin-4-yl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine (as per EP);N6-Cyclopropyl-9-{(1R,4S)-4-[(2,5-diamino-6-chloropyrimidin-4-yloxy)methyl]cyclopent-2-enyl}-9H-purine-2,6-diamine (as per USP)
Smiles : NC1=NC(NC2CC2)=C(N=CN3[C@@H]4C[C@H](COC5=NC(N)=NC(Cl)=C5N)C=C4)C3=N1
Inchi : InChI=1/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/i3D3,4D3
Synonym : O-Pyrimidine derivative abacavir (USP) ; Abacavir USP Related Compound D

Stability indicating RP-HPLC method development and validation for determination of abacavir sulphate in tablet dosage form

By Ithape, Aniket B.; Deshpande, Padmanabh B.; Shelke, PriyankanFrom International Journal of Pharmacy and Pharmaceutical Research (2020), 17(4), 670-680

A new stability indicating method was developed and validated for the simultaneous estimation of Lamivudine and Abacavir in tablet dosage form by RP-HPLC

By Rajamahanti, Santoshi G.; Annapurna, N.; Santosh, T.; Durga, B.; Raziya, S. K. – From Research Journal of Pharmaceutical, Biological and Chemical Sciences (2017), 8(3), 407-421

A validated stability-indicating RP-HPLC method for abacavir sulfate in the presence of degradation products, its process-related impurities and identification of oxidative degradant by LC-MS/MS

By Ragham, Pramod Kumar; Chandrasekhar, Kothapalli B.; Reddy, J. Rudraprasad; Kasturi, Krishna Mohan – From Indo American Journal of Pharmaceutical Research (2015), 5(1), 463-473

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