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Almotriptan EP Impurity E (Malic Acid)

Almotriptan EP Impurity E (Malic Acid)

Product Description
CAT No.
ALN-A087012
CAS No.
1189348-94-4
Mol. F.
C17H25N3O3S : C4H6O5
Mol. Wt.
351.5 : 134.1
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Chemical Name : N,N-Dimethyl-2-(5-((pyrrolidin-1-ylsulfonyl)methyl)-1H-indol-3-yl)ethan-1-amine oxide 2-hydroxysuccinate
Smiles : C[N](CCC1=CNC2=CC=C(C[S](=O)(N3CCCC3)=O)C=C12)(C)=O.OC(C(O)=O)CC(O)=O
Inchi : InChI=1S/C54H58N2O22/c1-19-41(58)25(55)11-31(74-19)76-29-15-51(68,13-23-35(29)49(66)39-37(45(23)62)43(60)21-7-5-9-27(71-3)33(21)47(39)64)53(70)18-73-54(17-57,78-53)52(69)14-24-36(30(16-52)77-32-12-26(56)42(59)20(2)75-32)50(67)40-38(46(24)63)44(61)22-8-6-10-28(72-4)34(22)48(40)65/h5-10,19-20,25-26,29-32,41-42,57-59,62-63,66-70H,11-18,55-56H2,1-4H3/t19-,20-,25-,26-,29-,30-,31-,32-,41+,42+,51-,52-,53?,54?/m0/s1
Synonym : Almotriptan USP Related Compound D ; Almotriptan N-Oxide

A validated reversed phase HPLC method for the determination of process-related impurities in almotriptan malate API

A. Phani Kumar a, V.R.L. Ganesh a, D.V. Subba Rao a, C. Anil a, B. Venugopala Rao a, V.S. Hariharakrishnan a,u2217, A. Suneetha b, B. Syama Sundar cnJournal of Pharmaceutical and Biomedical Analysis 46 (2008) 792u2013798

Stability-Indicating Reversed-Phase UHPLC Method Development and Characterization of Degradation Products of Almotriptan Maleate by LC-QTOF-MS/MS

B Saibaba, Ch Vishnuvardhan, P Johnsi Rani, N Satheesh Kumar – Journal of Chromatographic Science, Volume 56, Issue 1, January 2018, Pages 6–17

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