Amiodarone EP Impurity D

Product Description
CAT No.
ALN-A007005
CAS No.
1951-26-4
Mol. F.
C19H16I2O3
Mol. Wt.
546.1
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : (2-butylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone (as per EP) ; (2-Butylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl) methanone (as per USP)
Smiles : O=C(C1=C(CCCC)OC2=CC=CC=C12)C3=CC(I)=C(O)C(I)=C3
Inchi : InChI=1S/C25H30INO3.ClH/c1-4-7-11-23-24(19-10-8-9-12-21(19)30-23)25(28)18-13-14-22(20(26)17-18)29-16-15-27(5-2)6-3;/h8-10,12-14,17H,4-7,11,15-16H2,1-3H3;1H
Synonym : Amiodarone USP Related Compound D ; Amiodarone Metabolite B2 ;
Technical Data
Reference
Quality by design (QbD) based development and validation of an HPLC method for amiodarone hydrochloride and its impurities in the drug substance
S. Karmarkar u2217, X. Yang, R. Garber, A. Szajkovics, M. KoberdanJournal of Pharmaceutical and Biomedical Analysis 100 (2014) 167u2013174
Validation of a Stability-Indicating HPLC Method for the Determination of Amiodarone HCl and Its Related Substances in Amiodarone HCl Injection
Matthew J. Christopherson,
Stability-indicating HPLC method for determination of amiodarone hydrochloride and its impurities in tablets: a detailed forced degradation study
Kenton J. Yoder, and R. Brent Miller – Journal of liquid chromatography & related technologies vol. 27, No. 1, pp. 95–111, 2004
RFQ