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Apixaban Ethyl Ester Dimer Impurity

Apixaban Ethyl Ester Dimer Impurity

Product Description
CAT No.
ALN-A062096
CAS No.
NA
Mol. F.
C36H32N6O8
Mol. Wt.
676.7
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RFQ
Chemical Name : Dimethyl 3,6-bis(4-methoxyphenyl)-5-oxo-4-(4-(2-oxopiperidin-1-yl)phenyl)-3,4,5,6-tetrahydrodipyrazolo[3,4-b:4′,3′-d]pyridine-1,8-dicarboxylate
Smiles : COC(C=C1)=CC=C1N(N=C2C(OC)=O)C3=C2C(C(C(OC)=O)=NN4C5=CC=C(OC)C=C5)=C4C(N3C6=CC=C(N7CCCCC7=O)C=C6)=O
Inchi : InChI=1S/C17H19NO4/c1-18(21)7-6-17-10-3-5-13(20)16(17)22-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-,18-/m0/s1

Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults

YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmDnClinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1

Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban

Saradhi venkata ramana v.a,b

Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products

, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma – Int J Curr Pharm Res, Vol 12, Issue 2, 119-123

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