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Apixaban Impurity 18

Apixaban Impurity 18

Product Description
CAT No.
ALN-A062029
CAS No.
1643330-62-4
Mol. F.
C20H26ClN3O3
Mol. Wt.
391.9
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Chemical Name : 5-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)pentanamide
Smiles : ClCCCCC(NC1=CC=C(N2CCC=C(N3CCOCC3)C2=O)C=C1)=O
Inchi : InChI=1S/C20H19N5O3/c1-28-15-8-6-14(7-9-15)25-18-16(17(23-25)19(22)26)10-11-24(20(18)27)13-4-2-12(21)3-5-13/h2-9H,10-11,21H2,1H3,(H2,22,26)

Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults

YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmDnClinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1

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