Apixaban Impurity 22

Product Description
CAT No.
ALN-A062033
CAS No.
405872-78-8
Mol. F.
C11H13ClN2O3
Mol. Wt.
256.7
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : Ethyl (Z)-2-chloro-2-(2-(3-methoxyphenyl)hydrazono)acetate
Smiles : Cl/C(C(OCC)=O)=N\NC1=CC(OC)=CC=C1
Inchi : InChI=1S/C27H29ClN4O5/c1-3-37-27(35)24-22-15-17-31(19-9-7-18(8-10-19)29-23(33)6-4-5-16-28)26(34)25(22)32(30-24)20-11-13-21(36-2)14-12-20/h7-14H,3-6,15-17H2,1-2H3,(H,29,33)
Technical Data
Reference
Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmDnClinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma – Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
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