Apixaban Impurity 36

Product Description
CAT No.
ALN-A062051
CAS No.
503615-03-0
Mol. F.
C15H17N3O4
Mol. Wt.
303.3
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Technical Data
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Product Overview
Chemical Name : 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
Smiles : O=C1N(C2=CC=C([N](=O)=O)C=C2)CCC=C1N3CCOCC3
Inchi : InChI=1S/C22H20N4O6/c1-3-32-22(28)19-18-12-13-24(14-4-6-16(7-5-14)26(29)30)21(27)20(18)25(23-19)15-8-10-17(31-2)11-9-15/h4-11H,3,12-13H2,1-2H3
Technical Data
Reference
Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmDnClinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma – Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
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