Apixaban Impurity 43

Product Description
CAT No.
ALN-A062062
CAS No.
1998079-15-4
Mol. F.
C30H34N6O4
Mol. Wt.
542.6
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : (E)-1,1′-(Diazene-1,2-diylbis(4,1-phenylene))bis(3-morpholino-5,6-dihydropyridin-2(1H)-one)
Smiles : O=C1C(N2CCOCC2)=CCCN1C(C=C3)=CC=C3/N=N/C(C=C4)=CC=C4N5C(C(N6CCOCC6)=CCC5)=O
Inchi : InChI=1S/C18H15NO8S2.Na.O/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25;;/h1-12,18H,(H,20,21,22)(H,23,24,25);;/i;1-21;
Technical Data
Reference
Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmDnClinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma – Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
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