Apixaban Impurity 5

Product Description
CAT No.
ALN-A062016
CAS No.
NA
Mol. F.
C10H11ClN2O3
Mol. Wt.
242.7
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Technical Data
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Product Overview
Chemical Name : Ethyl (Z)-2-chloro-2-(2-(4-hydroxyphenyl)hydrazono)acetate
Smiles : O=C(OCC)/C(Cl)=N/NC1=CC=C(O)C=C1
Inchi : InChI=1S/C21H18N4O6/c1-2-31-21(28)18-17-11-12-23(13-3-5-15(6-4-13)25(29)30)20(27)19(17)24(22-18)14-7-9-16(26)10-8-14/h3-10,26H,2,11-12H2,1H3
Technical Data
Reference
Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmDnClinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma – Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
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