Apixaban Impurity 58

Product Description
CAT No.
ALN-A062080
CAS No.
881386-01-2
Mol. F.
C11H10Cl2N2O3
Mol. Wt.
289.1
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
Smiles : O=C1N(C2=CC=C([N](=O)=O)C=C2)CCCC1(Cl)Cl
Inchi : InChI=1S/C7H13ClO2/c1-2-10-7(9)5-3-4-6-8/h2-6H2,1H3
Technical Data
Reference
Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmDnClinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma – Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
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