Apixaban Impurity 65

Product Description
CAT No.
ALN-A062087
CAS No.
NA
Mol. F.
C16H16N2O2
Mol. Wt.
268.3
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Technical Data
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Product Overview
Chemical Name : 1-(4-(2-Oxopiperidin-1-yl)phenyl)pyridin-2(1H)-one
Smiles : O=C1C=CC=CN1C2=CC=C(N3C(CCCC3)=O)C=C2
Inchi : InChI=1S/C16H15N3O4/c20-15-5-1-2-10-18(15)14-4-3-11-17(16(14)21)12-6-8-13(9-7-12)19(22)23/h3-4,6-9,11H,1-2,5,10H2
Technical Data
Reference
Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmDnClinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma – Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
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