O-Desmethyl Apixaban

CAT No.

ALN-A062002

CAS No.

503612-76-8

Mol. F.

C24H23N5O4

Mol. Wt.

445.5

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Technical Data

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Product Overview

Chemical Name : 1-(4-Hydroxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

Smiles : O=C(N(C1=CC=C(N(CCCC2)C2=O)C=C1)CC3)C4=C3C(C(N)=O)=NN4C5=CC=C(O)C=C5

Inchi : InChI=1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32)

Synonym : 4-Demethoxy-4-hydroxy Apixaban

Technical Data

Reference

YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmDnClinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1

Saradhi venkata ramana v.a,b

, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma – Int J Curr Pharm Res, Vol 12, Issue 2, 119-123

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