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Aprepitant Impurity 4

Aprepitant Impurity 4

Product Description
CAT No.
ALN-A030043
CAS No.
380499-07-0
Mol. F.
C20H16F7NO2
Mol. Wt.
435.3
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Chemical Name : (R)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine
Smiles : C[C@H](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)O[C@@H]2C(C3=CC=C(F)C=C3)=NCCO2
Inchi : InChI=1S/C21H19F6NO3/c1-13(15-9-16(20(22,23)24)11-17(10-15)21(25,26)27)31-19-18(29)28(7-8-30-19)12-14-5-3-2-4-6-14/h2-6,9-11,13,19H,7-8,12H2,1H3/t13-,19-/m1/s1

Application of analytical quality by design principles for the determination of alkyl p-toluenesulfonates impurities in Aprepitant by HPLC. Validation using total-error concept

Constantinos K. Zacharis, Elli VastardinJournal of Pharmaceutical and Biomedical Analysis Volume 150, 20 February 2018, Pages 152-161

Characterization and Quantitation of Aprepitant Drug Substance Polymorphs by Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy

Roy Helmy,

Development and Optimization of Liquid Chromatography Analytical Methods by Using AQbD Principles: Overview and Recent Advances

George X. Zhou, Yadan W. Chen, Louis Crocker, Tao Wang, Robert M. Wenslow, Jr., and Anant Vailaya

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