Aripiprazole Desethylene Impurity

Product Description
CAT No.
ALN-A001022
CAS No.
1216394-63-6
Mol. F.
C21H25Cl2N3O2
Mol. Wt.
422.3
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 7-[4-[2-(2,3-Dichlorophenyl)amino-ethylamino]butoxy]-3,4-dihydro-2(1H)-quinolinone
Smiles : O=C1NC2=C(C=CC(OCCCCNCCNC3=CC=CC(Cl)=C3Cl)=C2)CC1
Inchi : InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-20(23(19)25)27-14-12-26(13-15-27)10-1-2-11-28-21-16-18(29)8-6-17(21)7-9-22(28)30/h3-6,8,16,29H,1-2,7,9-15H2
Technical Data
Reference
Formulation of aripiprazole-loaded pH-modulated solid dispersions via hot-melt extrusion technology: In vitro and In vivo studies
Haley McFall1 , Sandeep Sarabu1 , Vijaykumar Shankar1 , Suresh Bandari1 , S. Narasimha Murthy1 , Karl Kolter2 , Nigel Langley3 , Dong Wuk Kim4**, Michael A. RepkanInternational Journal of Pharmaceutics Volume 554, 10 January 2019, Pages 302-311
Molecular determinants of the intrinsic efficacy of the antipsychotic aripiprazole
Identification of Degradation Impurities in Aripiprazole Oral Solution Using LC-MS and Development of Validated Stability Indicating Method for Assay and Content of Two Preservatives by RP-HPLC
, Michael A. Repka – International Journal of Pharmaceutics Volume 554, 10 January 2019, Pages 302-311
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